Synovial tissue transcriptomes of long-standing rheumatoid arthritis are dominated by activated macrophages that reflect microbial stimulation

Advances in microbiome research suggest involvement in chronic inflammatory diseases such as rheumatoid arthritis (RA). Searching for initial trigger(s) in RA, we compared transcriptome profiles of highly inflamed RA synovial tissue (RA-ST) and osteoarthritis (OA)-ST with 182 selected reference tran...

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Detalles Bibliográficos
Autores principales: Smiljanovic, Biljana, Grützkau, Andreas, Sörensen, Till, Grün, Joachim R., Vogl, Thomas, Bonin, Marc, Schendel, Pascal, Stuhlmüller, Bruno, Claussnitzer, Anne, Hermann, Sandra, Ohrndorf, Sarah, Aupperle, Karlfried, Backhaus, Marina, Radbruch, Andreas, Burmester, Gerd R., Häupl, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7220941/
https://www.ncbi.nlm.nih.gov/pubmed/32404914
http://dx.doi.org/10.1038/s41598-020-64431-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7220941/
https://www.ncbi.nlm.nih.gov/pubmed/32404914
http://dx.doi.org/10.1038/s41598-020-64431-4

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