Cargando…
Synovial tissue transcriptomes of long-standing rheumatoid arthritis are dominated by activated macrophages that reflect microbial stimulation
Advances in microbiome research suggest involvement in chronic inflammatory diseases such as rheumatoid arthritis (RA). Searching for initial trigger(s) in RA, we compared transcriptome profiles of highly inflamed RA synovial tissue (RA-ST) and osteoarthritis (OA)-ST with 182 selected reference tran...
Autores principales: | Smiljanovic, Biljana, Grützkau, Andreas, Sörensen, Till, Grün, Joachim R., Vogl, Thomas, Bonin, Marc, Schendel, Pascal, Stuhlmüller, Bruno, Claussnitzer, Anne, Hermann, Sandra, Ohrndorf, Sarah, Aupperle, Karlfried, Backhaus, Marina, Radbruch, Andreas, Burmester, Gerd R., Häupl, Thomas |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7220941/ https://www.ncbi.nlm.nih.gov/pubmed/32404914 http://dx.doi.org/10.1038/s41598-020-64431-4 |
Ejemplares similares
-
Monocyte alterations in rheumatoid arthritis are dominated by preterm release from bone marrow and prominent triggering in the joint
por: Smiljanovic, Biljana, et al.
Publicado: (2018) -
Intestinal Microbiota Reduction Followed by Fasting Discloses Microbial Triggering of Inflammation in Rheumatoid Arthritis
por: Häupl, Thomas, et al.
Publicado: (2023) -
Cell-Specific Type I IFN Signatures in Autoimmunity and Viral Infection: What Makes the Difference?
por: Kyogoku, Chieko, et al.
Publicado: (2013) -
Upregulation of Immunoproteasome Subunits in Myositis Indicates Active Inflammation with Involvement of Antigen Presenting Cells, CD8 T-Cells and IFNγ
por: Ghannam, Khetam, et al.
Publicado: (2014) -
Unraveling complexity of rheumatoid synovial gene expression by comparison with purified leukocyte profiles
por: Häupl, T, et al.
Publicado: (2004)