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Stem Cell-Derived Human Striatal Progenitors Innervate Striatal Targets and Alleviate Sensorimotor Deficit in a Rat Model of Huntington Disease

Huntington disease (HD) is an inherited late-onset neurological disorder characterized by progressive neuronal loss and disruption of cortical and basal ganglia circuits. Cell replacement using human embryonic stem cells may offer the opportunity to repair the damaged circuits and significantly amel...

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Detalles Bibliográficos
Autores principales: Besusso, Dario, Schellino, Roberta, Boido, Marina, Belloli, Sara, Parolisi, Roberta, Conforti, Paola, Faedo, Andrea, Cernigoj, Manuel, Campus, Ilaria, Laporta, Angela, Bocchi, Vittoria Dickinson, Murtaj, Valentina, Parmar, Malin, Spaiardi, Paolo, Talpo, Francesca, Maniezzi, Claudia, Toselli, Mauro Giuseppe, Biella, Gerardo, Moresco, Rosa Maria, Vercelli, Alessandro, Buffo, Annalisa, Cattaneo, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7220987/
https://www.ncbi.nlm.nih.gov/pubmed/32302555
http://dx.doi.org/10.1016/j.stemcr.2020.03.018