Targeting the Multiple Physiologic Roles of VDAC With Steroids and Hydrophobic Drugs
There is accumulating evidence that endogenous steroids and non-polar drugs are involved in the regulation of mitochondrial physiology. Many of these hydrophobic compounds interact with the Voltage Dependent Anion Channel (VDAC). This major metabolite channel in the mitochondrial outer membrane (MOM...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221028/ https://www.ncbi.nlm.nih.gov/pubmed/32457654 http://dx.doi.org/10.3389/fphys.2020.00446 |