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Mosaic Somatic Gene Recombination as a Potentially Unifying Hypothesis for Alzheimer’s Disease
The recent identification of somatic gene recombination(SGR) in human neurons affecting the well-known Alzheimer’s disease (AD) pathogenic gene, amyloid precursor protein (APP), has implications for the normal and the diseased human brain. The amyloid hypothesis has been the prevailing theory for sp...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221065/ https://www.ncbi.nlm.nih.gov/pubmed/32457796 http://dx.doi.org/10.3389/fgene.2020.00390 |