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The Phosphatase CSW Controls Life Span by Insulin Signaling and Metabolism Throughout Adult Life in Drosophila

Noonan syndrome and related disorders are caused by mutations in genes encoding for proteins of the RAS-ERK1/2 signaling pathway, which affect development by enhanced ERK1/2 activity. However, the mutations’ effects throughout adult life are unclear. In this study, we identify that the protein most...

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Detalles Bibliográficos
Autores principales: Ruzzi, Leonardo R., Schilman, Pablo E., San Martin, Alvaro, Lew, Sergio E., Gelb, Bruce D., Pagani, Mario R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221067/
https://www.ncbi.nlm.nih.gov/pubmed/32457793
http://dx.doi.org/10.3389/fgene.2020.00364