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The Phosphatase CSW Controls Life Span by Insulin Signaling and Metabolism Throughout Adult Life in Drosophila
Noonan syndrome and related disorders are caused by mutations in genes encoding for proteins of the RAS-ERK1/2 signaling pathway, which affect development by enhanced ERK1/2 activity. However, the mutations’ effects throughout adult life are unclear. In this study, we identify that the protein most...
Autores principales: | Ruzzi, Leonardo R., Schilman, Pablo E., San Martin, Alvaro, Lew, Sergio E., Gelb, Bruce D., Pagani, Mario R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221067/ https://www.ncbi.nlm.nih.gov/pubmed/32457793 http://dx.doi.org/10.3389/fgene.2020.00364 |
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