Trefoil factors share a lectin activity that defines their role in mucus

The mucosal epithelium secretes a host of protective disulfide-rich peptides, including the trefoil factors (TFFs). The TFFs increase the viscoelasticity of the mucosa and promote cell migration, though the molecular mechanisms underlying these functions have remained poorly defined. Here, we demons...

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Detalles Bibliográficos
Autores principales: Järvå, Michael A., Lingford, James P., John, Alan, Soler, Niccolay Madiedo, Scott, Nichollas E., Goddard-Borger, Ethan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221086/
https://www.ncbi.nlm.nih.gov/pubmed/32404934
http://dx.doi.org/10.1038/s41467-020-16223-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221086/
https://www.ncbi.nlm.nih.gov/pubmed/32404934
http://dx.doi.org/10.1038/s41467-020-16223-7

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