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Trefoil factors share a lectin activity that defines their role in mucus
The mucosal epithelium secretes a host of protective disulfide-rich peptides, including the trefoil factors (TFFs). The TFFs increase the viscoelasticity of the mucosa and promote cell migration, though the molecular mechanisms underlying these functions have remained poorly defined. Here, we demons...
Autores principales: | Järvå, Michael A., Lingford, James P., John, Alan, Soler, Niccolay Madiedo, Scott, Nichollas E., Goddard-Borger, Ethan D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221086/ https://www.ncbi.nlm.nih.gov/pubmed/32404934 http://dx.doi.org/10.1038/s41467-020-16223-7 |
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