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Molecular determinants underlying functional innovations of TBP and their impact on transcription initiation

TATA-box binding protein (TBP) is required for every single transcription event in archaea and eukaryotes. It binds DNA and harbors two repeats with an internal structural symmetry that show sequence asymmetry. At various times in evolution, TBP has acquired multiple interaction partners and differe...

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Detalles Bibliográficos
Autores principales: Ravarani, Charles N. J., Flock, Tilman, Chavali, Sreenivas, Anandapadamanaban, Madhanagopal, Babu, M. Madan, Balaji, Santhanam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221094/
https://www.ncbi.nlm.nih.gov/pubmed/32404905
http://dx.doi.org/10.1038/s41467-020-16182-z