BAF60a deficiency uncouples chromatin accessibility and cold sensitivity from white fat browning

Brown and beige fat share a remarkably similar transcriptional program that supports fuel oxidation and thermogenesis. The chromatin-remodeling machinery that governs genome accessibility and renders adipocytes poised for thermogenic activation remains elusive. Here we show that BAF60a, a subunit of...

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Detalles Bibliográficos
Autores principales: Liu, Tongyu, Mi, Lin, Xiong, Jing, Orchard, Peter, Yu, Qi, Yu, Lei, Zhao, Xu-Yun, Meng, Zhuo-Xian, Parker, Stephen C. J., Lin, Jiandie D., Li, Siming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221096/
https://www.ncbi.nlm.nih.gov/pubmed/32404872
http://dx.doi.org/10.1038/s41467-020-16148-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221096/
https://www.ncbi.nlm.nih.gov/pubmed/32404872
http://dx.doi.org/10.1038/s41467-020-16148-1

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