Rheb1 protects against cisplatin-induced tubular cell death and acute kidney injury via maintaining mitochondrial homeostasis

Ras homolog enriched in brain (Rheb1), a small GTPase, plays a crucial role in regulating cell growth, differentiation, and survival. However, the role and mechanisms for Rheb1 in tubular cell survival and acute kidney injury (AKI) remain unexplored. Here we found that Rheb1 signaling was activated...

Descripción completa

Detalles Bibliográficos
Autores principales: Lu, Qingmiao, Wang, Mingjie, Gui, Yuan, Hou, Qing, Gu, Mengru, Liang, Yan, Xiao, Bo, Zhao, Allan Zijian, Dai, Chunsun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221100/
https://www.ncbi.nlm.nih.gov/pubmed/32404875
http://dx.doi.org/10.1038/s41419-020-2539-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221100/
https://www.ncbi.nlm.nih.gov/pubmed/32404875
http://dx.doi.org/10.1038/s41419-020-2539-4

Ejemplares similares