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An FGFR/AKT/SOX2 Signaling Axis Controls Pancreatic Cancer Stemness

Cancer stemness is associated with high malignancy and low differentiation, as well as therapeutic resistance of tumors including pancreatic ductal adenocarcinoma (PDAC). Fibroblast growth factors (FGFs) exert pleiotropic effects on a variety of cellular processes and functions including embryonic s...

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Detalles Bibliográficos
Autores principales: Quan, Mei-Yu, Guo, Qiang, Liu, Jiayu, Yang, Ruo, Bai, Jing, Wang, Wei, Cai, Yaxin, Han, Rui, Lv, Yu-Qing, Ding, Li, Billadeau, Daniel D., Lou, Zhenkun, Bellusci, Saverio, Li, Xiaokun, Zhang, Jin-San
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221133/
https://www.ncbi.nlm.nih.gov/pubmed/32457900
http://dx.doi.org/10.3389/fcell.2020.00287