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Cortical Thymocytes Along With Their Selecting Ligands Are Required for the Further Thymic Maturation of NKT Cells in Mice

Following positive selection, NKT cell precursors enter an “NK-like” program and progress from an NK(–) to an NK(+) maturational stage to give rise to NKT1 cells. Maturation takes place in the thymus or after emigration of NK(–) NKT cells to the periphery. In this study, we followed the fate of inje...

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Detalles Bibliográficos
Autores principales: Klibi, Jihene, Benlagha, Kamel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221135/
https://www.ncbi.nlm.nih.gov/pubmed/32457751
http://dx.doi.org/10.3389/fimmu.2020.00815