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Cysteine Depletion, a Key Action to Challenge Cancer Cells to Ferroptotic Cell Death

Cancer cells are characterized as highly proliferative at the expense of enhancement of metabolic rate. Consequently, cancer cells rely on antioxidant defenses to overcome the associated increased production of reactive oxygen species (ROS). The reliance of tumor metabolism on amino acids, especiall...

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Detalles Bibliográficos
Autores principales: Daher, Boutaina, Vučetić, Milica, Pouysségur, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221143/
https://www.ncbi.nlm.nih.gov/pubmed/32457843
http://dx.doi.org/10.3389/fonc.2020.00723