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Prevalence and Incidence of Non-neutralizing Antibodies in Congenital Hemophilia A— A Systematic Review and Meta-Analysis

Objectives: In hemophilia A the presence of non-neutralizing antibodies (NNAs) against Factor VIII (FVIII) may predict the development of neutralizing antibodies (inhibitors) and accelerate the clearance of administrated FVIII concentrates. This systematic review aimed to assess: (1) the prevalence...

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Detalles Bibliográficos
Autores principales: Abdi, A., Bordbar, M. R., Hassan, S., Rosendaal, F. R., van der Bom, J. G., Voorberg, J., Fijnvandraat, K., Gouw, S. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221178/
https://www.ncbi.nlm.nih.gov/pubmed/32457734
http://dx.doi.org/10.3389/fimmu.2020.00563