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The Streptococcal Protease SpeB Antagonizes the Biofilms of the Human Pathogen Staphylococcus aureus USA300 through Cleavage of the Staphylococcal SdrC Protein

Streptococcus pyogenes, or group A Streptococcus (GAS), is both a pathogen and an asymptomatic colonizer of human hosts and produces a large number of surface-expressed and secreted factors that contribute to a variety of infection outcomes. The GAS-secreted cysteine protease SpeB has been well stud...

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Detalles Bibliográficos
Autores principales: Carothers, Katelyn E., Liang, Zhong, Mayfield, Jeffrey, Donahue, Deborah L., Lee, Mijoon, Boggess, Bill, Ploplis, Victoria A., Castellino, Francis J., Lee, Shaun W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221255/
https://www.ncbi.nlm.nih.gov/pubmed/32205460
http://dx.doi.org/10.1128/JB.00008-20