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ASCT2 overexpression is associated with poor survival of OSCC patients and ASCT2 knockdown inhibited growth of glutamine‐addicted OSCC cells

BACKGROUND: Alanine‐serine‐cysteine transporter 2 (ASCT2), a major glutamine transporter, is essential for cell growth and tumor development in a variety of cancers. However, the clinicopathological significance and pathological role of ASCT2 in OSCC (oral squamous cell carcinoma) lesions remain unc...

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Detalles Bibliográficos
Autores principales: Luo, Yijun, Li, Wei, Ling, Zihang, Hu, Qinchao, Fan, Zhen, Cheng, Bin, Tao, Xiaoan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221297/
https://www.ncbi.nlm.nih.gov/pubmed/32162845
http://dx.doi.org/10.1002/cam4.2965