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Favorable Anakinra Responses in Severe Covid-19 Patients with Secondary Hemophagocytic Lymphohistiocytosis

Dysregulation of inflammation is hypothesized to play a crucial role in the severe complications of COVID-19, with the IL-1/IL-6 pathway being central. Here, we report on the treatment of eight severe COVID-19 pneumonia patients—seven hospitalized in intensive care units (ICUs) in Greece and one non...

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Detalles Bibliográficos
Autores principales: Dimopoulos, George, de Mast, Quirijn, Markou, Nikolaos, Theodorakopoulou, Maria, Komnos, Apostolos, Mouktaroudi, Maria, Netea, Mihai G., Spyridopoulos, Themistoklis, Verheggen, Rebecca J., Hoogerwerf, Jacobien, Lachana, Alexandra, van de Veerdonk, Frank L., Giamarellos-Bourboulis, Evangelos J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221383/
https://www.ncbi.nlm.nih.gov/pubmed/32411313
http://dx.doi.org/10.1016/j.chom.2020.05.007