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Inferring the direction of a causal link and estimating its effect via a Bayesian Mendelian randomization approach
The use of genetic variants as instrumental variables – an approach known as Mendelian randomization – is a popular epidemiological method for estimating the causal effect of an exposure (phenotype, biomarker, risk factor) on a disease or health-related outcome from observational data. Instrumental...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
SAGE Publications
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221461/ https://www.ncbi.nlm.nih.gov/pubmed/31146640 http://dx.doi.org/10.1177/0962280219851817 |