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Inhibition of the Spectraplakin Protein Microtubule Actin Crosslinking Factor 1 Sensitizes Glioblastomas to Radiation

BACKGROUND: Microtubule actin crosslinking factor 1 (MACF1) is a spectraplakin cytoskeletal crosslinking protein whose function and role in cancer biology has lacked investigation. Recent studies have identified MACF1 as a novel target in glioblastomas expressed in tissue from tumor patient explants...

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Detalles Bibliográficos
Autores principales: Bonner, Kala, Borlay, Danielle, Kutten, Orica, Quick, Quincy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Brain Tumor Society; The Korean Society for Neuro-Oncology; The Korean Society for Pediatric Neuro-Oncology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221465/
https://www.ncbi.nlm.nih.gov/pubmed/32390353
http://dx.doi.org/10.14791/btrt.2020.8.e1