Synthesis and Evaluation of [(18)F]FEtLos and [(18)F]AMBF(3)Los as Novel (18)F-Labelled Losartan Derivatives for Molecular Imaging of Angiotensin II Type 1 Receptors

Losartan is widely used in clinics to treat cardiovascular related diseases by selectively blocking the angiotensin II type 1 receptors (AT(1)Rs), which regulate the renin-angiotensin system (RAS). Therefore, monitoring the physiological and pathological biodistribution of AT(1)R using positron emis...

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Detalles Bibliográficos
Autores principales: Sahylí Ortega Pijeira, Martha, Sérgio Gonçalves Nunes, Paulo, Nascimento dos Santos, Sofia, Zhang, Zhengxing, Pérez Nario, Arian, Araujo Perini, Efrain, Miguel Turato, Walter, Rodríguez Riera, Zalua, Chammas, Roger, H. Elsinga, Philip, Lin, Kuo-Shyan, Carvalho, Ivone, Soares Bernardes, Emerson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221519/
https://www.ncbi.nlm.nih.gov/pubmed/32325695
http://dx.doi.org/10.3390/molecules25081872

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221519/
https://www.ncbi.nlm.nih.gov/pubmed/32325695
http://dx.doi.org/10.3390/molecules25081872

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