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Targeting Trypanothione Reductase, a Key Enzyme in the Redox Trypanosomatid Metabolism, to Develop New Drugs against Leishmaniasis and Trypanosomiases

The protozoans Leishmania and Trypanosoma, belonging to the same Trypanosomatidae family, are the causative agents of Leishmaniasis, Chagas disease, and human African trypanosomiasis. Overall, these infections affect millions of people worldwide, posing a serious health issue as well as socio-econom...

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Detalles Bibliográficos
Autores principales: Battista, Theo, Colotti, Gianni, Ilari, Andrea, Fiorillo, Annarita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221613/
https://www.ncbi.nlm.nih.gov/pubmed/32326257
http://dx.doi.org/10.3390/molecules25081924