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Nanoparticle-Mediated Gene Silencing for Sensitization of Lung Cancer to Cisplatin Therapy

Platinum-based chemotherapy remains a mainstay treatment for the management of advanced non-small cell lung cancer. A key cellular factor that contributes to sensitivity to platinums is the 5′-3′ structure-specific endonuclease excision repair cross-complementation group 1 (ERCC1)/ xeroderma pigment...

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Detalles Bibliográficos
Autores principales: Feldmann, Daniel P., Heyza, Joshua, Zimmermann, Christoph M., Patrick, Steve M., Merkel, Olivia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221615/
https://www.ncbi.nlm.nih.gov/pubmed/32344513
http://dx.doi.org/10.3390/molecules25081994