Concise Synthesis of Catechin Metabolites 5-(3′,4′-Dihydroxyphenyl)-γ-valerolactones (DHPV) in Optically Pure Form and Their Stereochemical Effects on Skin Wrinkle-Reducing Activities

A concise and scalable synthetic route for optically pure (4S) and (4R)-5-(3′,4′-dihydroxyphenyl)-γ-valerolactones (DHPVs), catechin metabolites, has been developed via the efficient construction of a γ-valerolactone moiety from hexenol. Noticeably, the different skin wrinkle-reducing activities of...

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Detalles Bibliográficos
Autores principales: Hur, Joonseong, Kim, A-Ram, Kim, Hyun Su, Lim, Changjin, Kim, Taewoo, Kim, Tae-Aug, Sim, Jaehoon, Suh, Young-Ger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221625/
https://www.ncbi.nlm.nih.gov/pubmed/32340245
http://dx.doi.org/10.3390/molecules25081970

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221625/
https://www.ncbi.nlm.nih.gov/pubmed/32340245
http://dx.doi.org/10.3390/molecules25081970

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