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Effects of Length and Loop Composition on Structural Diversity and Similarity of (G(3)TG(3)N(m)G(3)TG(3)) G-Quadruplexes

A G-rich sequence containing three loops to connect four G-tracts with each ≥2 guanines can possibly form G-quadruplex structures. Given that all G-quadruplex structures comprise the stacking of G-quartets, the loop sequence plays a major role on their folding topology and thermal stability. Here ci...

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Detalles Bibliográficos
Autores principales: Li, Jie, Chu, I-Te, Yeh, Ting-An, Chen, De-Yu, Wang, Chiung-Lin, Chang, Ta-Chau
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221631/
https://www.ncbi.nlm.nih.gov/pubmed/32294984
http://dx.doi.org/10.3390/molecules25081779