Syntheses and Structure–Activity Relationships in Growth Inhibition Activity against Human Cancer Cell Lines of 12 Substituted Berberine Derivatives

In this study, quaternary berberine chloride is used as a lead compound to design and synthesize a series of berberine-12-amine derivatives to evaluate the growth inhibition activity against human cancer cell lines. Forty-two compounds of several series were obtained. The quaternary berberine-12-N,N...

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Detalles Bibliográficos
Autores principales: Wang, Bo, Deng, An-Jun, Li, Zhi-Hong, Wang, Nan, Qin, Hai-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221678/
https://www.ncbi.nlm.nih.gov/pubmed/32325679
http://dx.doi.org/10.3390/molecules25081871

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221678/
https://www.ncbi.nlm.nih.gov/pubmed/32325679
http://dx.doi.org/10.3390/molecules25081871

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