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Tumor-Targeted Delivery of the p53-Activating Peptide VIP116 with PEG-Stabilized Lipodisks

Stapled peptides targeting the interaction between p53 and its negative regulators MDM2 and MDM4 have exhibited great potential as anti-cancer drugs, albeit with room for improvement in formulation and tumor specificity. Lipid bilayer disks (lipodisks) have emerged as promising drug nanocarriers and...

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Detalles Bibliográficos
Autores principales: Lundsten, Sara, Hernández, Víctor Agmo, Gedda, Lars, Sarén, Tina, Brown, Christopher J., Lane, David P., Edwards, Katarina, Nestor, Marika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221704/
https://www.ncbi.nlm.nih.gov/pubmed/32325827
http://dx.doi.org/10.3390/nano10040783