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Synthetic Kavalactone Analogues with Increased Potency and Selective Anthelmintic Activity against Larvae of Haemonchus contortus In Vitro

Kava extract, an aqueous rhizome emulsion of the plant Piper methysticum, has been used for centuries by Pacific Islanders as a ceremonial beverage, and has been sold as an anxiolytic agent for some decades. Kavalactones are a major constituent of kava extract. In a previous investigation, we had id...

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Detalles Bibliográficos
Autores principales: Herath, H.M.P. Dilrukshi, Taki, Aya C., Nguyen, Nghi, Garcia-Bustos, José, Hofmann, Andreas, Wang, Tao, Ma, Guangxu, Chang, Bill C.H., Jabbar, Abdul, Sleebs, Brad E., Gasser, Robin B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221733/
https://www.ncbi.nlm.nih.gov/pubmed/32344703
http://dx.doi.org/10.3390/molecules25082004