Metabolism and Pharmacokinetics of SP-8356, a Novel (1S)-(−)-Verbenone Derivative, in Rats and Dogs and Its Implications in Humans

(1S,5R)-4-((E)-3,4-dihydroxy-5-methoxystryryl)-6,6-dimethylbicylco[3.1.1]hept-3-en-2-one (SP-8356) is a novel (1S)-(−)-verbenone derivative that is currently in preclinical development for the treatment of ischemic stroke and atherosclerosis. This report aimed at characterization of the metabolism a...

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Detalles Bibliográficos
Autores principales: Zhou, Yuanyuan, Oh, Mun Hwan, Kim, Yeon Joon, Kim, Eun-yeong, Kang, Jinhong, Chung, Sung, Ju, Chung, Kim, Won-Ki, Lee, Kiho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221793/
https://www.ncbi.nlm.nih.gov/pubmed/32294954
http://dx.doi.org/10.3390/molecules25081775

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221793/
https://www.ncbi.nlm.nih.gov/pubmed/32294954
http://dx.doi.org/10.3390/molecules25081775

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