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Polypseudorotaxanes of Pluronic® F127 with Combinations of α- and β-Cyclodextrins for Topical Formulation of Acyclovir

Acyclovir (ACV) is one of the most used antiviral drugs for the treatment of herpes simplex virus infections and other relevant mucosal infections caused by viruses. Nevertheless, the low water solubility of ACV limits both its bioavailability and antiviral performance. The combination of block copo...

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Detalles Bibliográficos
Autores principales: Di Donato, Cristina, Iacovino, Rosa, Isernia, Carla, Malgieri, Gaetano, Varela-Garcia, Angela, Concheiro, Angel, Alvarez-Lorenzo, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221812/
https://www.ncbi.nlm.nih.gov/pubmed/32230723
http://dx.doi.org/10.3390/nano10040613