5-Oxo-hexahydroquinoline Derivatives and Their Tetrahydroquinoline Counterparts as Multidrug Resistance Reversal Agents

Cancer is a leading cause of death worldwide. Multidrug resistance (MDR) is a main reason of chemotherapy failure in many patients and is often related to overexpression of ATP-binding cassette (ABC) transporters, including P-glycoprotein (P-gp/ABCB1). Agents that are capable of modulation of the ac...

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Detalles Bibliográficos
Autores principales: Shahraki, Omolbanin, Khoshneviszadeh, Mehdi, Dehghani, Mojtaba, Mohabbati, Maryam, Tavakkoli, Marjan, Saso, Luciano, Edraki, Najmeh, Firuzi, Omidreza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221826/
https://www.ncbi.nlm.nih.gov/pubmed/32316291
http://dx.doi.org/10.3390/molecules25081839

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221826/
https://www.ncbi.nlm.nih.gov/pubmed/32316291
http://dx.doi.org/10.3390/molecules25081839

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