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Organic Salts of Pharmaceutical Impurity p-Aminophenol

The presence of impurities can drastically affect the efficacy and safety of pharmaceutical entities. p-Aminophenol (PAP) is one of the main impurities of paracetamol (PA) that can potentially show toxic effects such as maternal toxicity and nephrotoxicity. The removal of PAP from PA is challenging...

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Detalles Bibliográficos
Autores principales: Khandavilli, U. B. Rao, Keshavarz, Leila, Skořepová, Eliška, Steendam, René R. E., Frawley, Patrick J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221883/
https://www.ncbi.nlm.nih.gov/pubmed/32326160
http://dx.doi.org/10.3390/molecules25081910