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Targeting the “PVR–TIGIT axis” with immune checkpoint therapies

Checkpoint inhibitors have become an efficient way to treat cancers. Indeed, anti-CTLA-4, anti-PD1, and anti-PDL-1 antibodies are now used as therapies for cancers. However, while these therapies are very efficient in certain tumors, they remain poorly efficient in others. This might be explained by...

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Detalles Bibliográficos
Autores principales: Gorvel, Laurent, Olive, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7222031/
https://www.ncbi.nlm.nih.gov/pubmed/32489646
http://dx.doi.org/10.12688/f1000research.22877.1