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Modulation of the leptin receptors expression in breast cancer cell lines exposed to leptin and tamoxifen

One of the factors that has increased the incidence and worse prognosis of breast cancer is obesity. In this condition, high amounts of leptin are secreted, which have proliferative, mitogenic, antiapoptotic, and proinflammatory activity that may be antagonistic to treatment with tamoxifen, consider...

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Detalles Bibliográficos
Autores principales: Linares, Rodolfo López, Benítez, Jonnathan Guadalupe Santillán, Reynoso, Mariana Ortiz, Romero, Carlos González, Sandoval-Cabrera, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7222035/
https://www.ncbi.nlm.nih.gov/pubmed/31844100
http://dx.doi.org/10.1038/s41598-019-55674-x