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AKR1B1-Induced Epithelial–Mesenchymal Transition Mediated by RAGE-Oxidative Stress in Diabetic Cataract Lens

Purpose: Cataracts are a major cause of visual acuity deterioration in diabetes mellitus (DM) in developed and developing countries. Studies have demonstrated that overproduction of AKR1B1 and receptor for advanced glycation end products (RAGE) plays a major role in the pathogenesis of diabetic cata...

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Detalles Bibliográficos
Autores principales: Wu, Tsung-Tien, Chen, Ying-Ying, Chang, Hui-Yu, Kung, Ya-Hsin, Tseng, Ching-Jiunn, Cheng, Pei-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7222180/
https://www.ncbi.nlm.nih.gov/pubmed/32218152
http://dx.doi.org/10.3390/antiox9040273