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CXCR4 and JUNB double-positive disseminated tumor cells are detected frequently in breast cancer patients at primary diagnosis

BACKGROUND: The chemokine receptor CXCR4 and the transcription factor JUNB, expressed on a variety of tumor cells, seem to play an important role in the metastatic process. Since disseminated tumor cells (DTCs) in the bone marrow (BM) have been associated with worse outcomes, we evaluated the expres...

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Detalles Bibliográficos
Autores principales: Kallergi, Galatea, Hoffmann, Oliver, Bittner, Ann-Kathrin, Papadimitriou, Lina, Katsarou, Spyridoula D., Zacharopoulou, Nefeli, Zervakis, Michalis, Sfakianakis, Stelios, Stournaras, Christos, Georgoulias, Vassilis, Kimmig, Rainer, Kasimir-Bauer, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7222234/
https://www.ncbi.nlm.nih.gov/pubmed/32426042
http://dx.doi.org/10.1177/1758835919895754