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Targeting a cysteine protease from a pathobiont alleviates experimental arthritis

BACKGROUND: Several lines of evidence suggest that the pathobiont Porphyromonas gingivalis is involved in the development and/or progression of auto-inflammatory diseases. This bacterium produces cysteine proteases, such as gingipain RgpA, endowed with the potential to induce significant bone loss i...

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Detalles Bibliográficos
Autores principales: Peng, Hsin-Yi, Chen, Shih-Yao, Siao, Shih-Hong, Chang, Jinghua Tsai, Xue, Ting-Yin, Lee, Yi-Hsuan, Jan, Ming-Shiou, Tsay, Gregory J., Zouali, Moncef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7222327/
https://www.ncbi.nlm.nih.gov/pubmed/32410713
http://dx.doi.org/10.1186/s13075-020-02205-z