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Targeting a cysteine protease from a pathobiont alleviates experimental arthritis
BACKGROUND: Several lines of evidence suggest that the pathobiont Porphyromonas gingivalis is involved in the development and/or progression of auto-inflammatory diseases. This bacterium produces cysteine proteases, such as gingipain RgpA, endowed with the potential to induce significant bone loss i...
Autores principales: | Peng, Hsin-Yi, Chen, Shih-Yao, Siao, Shih-Hong, Chang, Jinghua Tsai, Xue, Ting-Yin, Lee, Yi-Hsuan, Jan, Ming-Shiou, Tsay, Gregory J., Zouali, Moncef |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7222327/ https://www.ncbi.nlm.nih.gov/pubmed/32410713 http://dx.doi.org/10.1186/s13075-020-02205-z |
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