Triple Combination of Ascorbate, Menadione and the Inhibition of Peroxiredoxin-1 Produces Synergistic Cytotoxic Effects in Triple-Negative Breast Cancer Cells

Triple-negative breast cancer (TNBC) is an aggressive form of mammary malignancy currently without satisfactory systemic treatment options. Agents generating reactive oxygen species (ROS), such as ascorbate (Asc) and menadione (Men), especially applied in combination, have been proposed as an altern...

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Detalles Bibliográficos
Autores principales: Bajor, Malgorzata, Graczyk-Jarzynka, Agnieszka, Marhelava, Katsiaryna, Kurkowiak, Malgorzata, Rahman, Arman, Aura, Claudia, Russell, Niamh, Zych, Agata O., Firczuk, Malgorzata, Winiarska, Magdalena, Gallagher, William M., Zagozdzon, Radoslaw
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7222372/
https://www.ncbi.nlm.nih.gov/pubmed/32316111
http://dx.doi.org/10.3390/antiox9040320

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7222372/
https://www.ncbi.nlm.nih.gov/pubmed/32316111
http://dx.doi.org/10.3390/antiox9040320

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