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Sustainable Synthesis of p-Hydroxycinnamic Diacids through Proline-Mediated Knoevenagel Condensation in Ethanol: An Access to Potent Phenolic UV Filters and Radical Scavengers

p-Hydroxycinnamic diacids are reaction intermediates of the classical Knoevenagel–Doebner condensation between malonic acid and benzaldehydes. As they are generally obtained in low yields, they remain relatively under-studied and under-exploited. Herein, we developed and optimized a sustainable synt...

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Detalles Bibliográficos
Autores principales: Rioux, Benjamin, Peyrot, Cédric, Mention, Matthieu M., Brunissen, Fanny, Allais, Florent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7222392/
https://www.ncbi.nlm.nih.gov/pubmed/32325641
http://dx.doi.org/10.3390/antiox9040331