Potential Benefits of Nrf2/Keap1 Targeting in Pancreatic Islet Cell Transplantation

Permanent pancreatic islet cell destruction occurs in type 1 diabetes mellitus (T1DM) through the infiltration of inflammatory cells and cytokines. Loss of β-cell integrity secondary to oxidation leads to an inability to appropriately synthesize and secrete insulin. Allogenic islet cell transplantat...

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Detalles Bibliográficos
Autores principales: Jarrin Lopez, Alberto, Lau, Hien, Li, Shiri, Ichii, Hirohito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7222398/
https://www.ncbi.nlm.nih.gov/pubmed/32316115
http://dx.doi.org/10.3390/antiox9040321

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7222398/
https://www.ncbi.nlm.nih.gov/pubmed/32316115
http://dx.doi.org/10.3390/antiox9040321

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