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Potential Benefits of Nrf2/Keap1 Targeting in Pancreatic Islet Cell Transplantation
Permanent pancreatic islet cell destruction occurs in type 1 diabetes mellitus (T1DM) through the infiltration of inflammatory cells and cytokines. Loss of β-cell integrity secondary to oxidation leads to an inability to appropriately synthesize and secrete insulin. Allogenic islet cell transplantat...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7222398/ https://www.ncbi.nlm.nih.gov/pubmed/32316115 http://dx.doi.org/10.3390/antiox9040321 |