Frameshift peptides alter the properties of truncated FUS proteins in ALS-FUS

Mutations in the FUS gene cause a subset of ALS cases (ALS-FUS). The majority of FUS mutations are missense mutations affecting the nuclear localisation signal (NLS) of FUS. In addition, a number of frameshift mutations which result in complete NLS deletion have been described. Patients bearing fram...

Descripción completa

Detalles Bibliográficos
Autores principales: An, Haiyan, Rabesahala de Meritens, Camille, Buchman, Vladimir L., Shelkovnikova, Tatyana A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Micro Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7222445/
https://www.ncbi.nlm.nih.gov/pubmed/32404191
http://dx.doi.org/10.1186/s13041-020-00618-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7222445/
https://www.ncbi.nlm.nih.gov/pubmed/32404191
http://dx.doi.org/10.1186/s13041-020-00618-0

Ejemplares similares