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Lanthanum Chloride Causes Neurotoxicity in Rats by Upregulating miR-124 Expression and Targeting PIK3CA to Regulate the PI3K/Akt Signaling Pathway

BACKGROUND: Lanthanum (La) exposure can cause central nervous system (CNS) damage and dysfunction in children, seriously affecting intellectual development. miR-124 plays an important role in the development of the nervous system. We exposed rats to a La environment then observed the rats' lear...

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Detalles Bibliográficos
Autores principales: Zheng, Linlin, Zhang, Jinhui, Yu, Shengjin, Ding, Zhe, Song, Heling, Wang, Yan, Li, Yicui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7222569/
https://www.ncbi.nlm.nih.gov/pubmed/32461997
http://dx.doi.org/10.1155/2020/5205142