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Development of Population and Bayesian Models for Applied Use in Patients Receiving Cefepime

BACKGROUND AND OBJECTIVE: Understanding pharmacokinetic disposition of cefepime, a β-lactam antibiotic, is crucial for developing regimens to achieve optimal exposure and improved clinical outcomes. This study sought to develop and evaluate a unified population pharmacokinetic model in both pediatri...

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Detalles Bibliográficos
Autores principales: Liu, Jiajun, Neely, Michael, Lipman, Jeffrey, Sime, Fekade, Roberts, Jason A., Kiel, Patrick J., Avedissian, Sean N., Rhodes, Nathaniel J., Scheetz, Marc H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7222999/
https://www.ncbi.nlm.nih.gov/pubmed/32140940
http://dx.doi.org/10.1007/s40262-020-00873-3