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Macrophage-like THP-1 cells show effective uptake of silica nanoparticles carrying inactivated diphtheria toxoid for vaccination

Nanoparticles may be used in vaccinology as an antigen delivery and/or an immunostimulant to enhance immunity. Porous silica has been identified as an effective adjuvant for more than a decade, and we have therefore investigated the take up rate by an immortalized macrophage-like cell line of a numb...

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Detalles Bibliográficos
Autores principales: Huang, Xinyue, Cavalcante, Danielle Paixão, Townley, Helen E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7223038/
https://www.ncbi.nlm.nih.gov/pubmed/32435151
http://dx.doi.org/10.1007/s11051-019-4720-1