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Different effects of acetyl-CoA carboxylase inhibitor TOFA on airway inflammation and airway resistance in a mice model of asthma

BACKGROUND AND OBJECTIVE: Acetyl CoA carboxylase (ACC) regulates the differentiation of Th1, Th2, Th17 cells and Treg cells, which play a critical role in airway inflammation of asthma. Here we investigated the role of ACC in the pathogenesis of asthma. METHODS: Chicken Ovalbumin-sensitized and -cha...

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Detalles Bibliográficos
Autores principales: Zhu, Fang-fang, Wang, Yi-min, He, Guang-zhen, Chen, Yi-fei, Gao, Ya-dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7223088/
https://www.ncbi.nlm.nih.gov/pubmed/32048254
http://dx.doi.org/10.1007/s43440-019-00027-8