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Nicorandil, a K(ATP) Channel Opener, Attenuates Ischemia–Reperfusion Injury in Isolated Rat Lungs

PURPOSE: Nicorandil is a hybrid between nitrates and K(ATP) channel opener activators. The aim of this study was to evaluate the nicorandil’s effects on ischemia–reperfusion (IR) lung injury and examine the mechanism of its effects. METHODS: Isolated rat lungs were divided into 6 groups. In the sham...

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Detalles Bibliográficos
Autores principales: Abe, Kyoko, Horiguchi, Takashi, Enzan, Keiji, Masaki, Yoko, Nishikawa, Toshiaki, Kimura, Tetsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7223246/
https://www.ncbi.nlm.nih.gov/pubmed/32086560
http://dx.doi.org/10.1007/s00408-020-00339-0