Xentry-Gap19 inhibits Connexin43 hemichannel opening especially during hypoxic injury

Hypoxic injury results in cell death, tissue damage and activation of inflammatory pathways. This is mediated by pathological Connexin43 (Cx43) hemichannel (HC) opening resulting in osmotic and ionic imbalances as well as cytokine production perpetuating the inflammatory environment. Gap19 is an int...

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Detalles Bibliográficos
Autores principales: Coutinho, Frazer P., Green, Colin R., Acosta, Monica L., Rupenthal, Ilva D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7223318/
https://www.ncbi.nlm.nih.gov/pubmed/32318976
http://dx.doi.org/10.1007/s13346-020-00763-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7223318/
https://www.ncbi.nlm.nih.gov/pubmed/32318976
http://dx.doi.org/10.1007/s13346-020-00763-y

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